For centuries, Agaricus blazei Murill has been a treasured component of traditional medicine in Brazil and Japan. Revered for its remarkable health benefits, this mushroom has been a symbol of vitality and wellness. Healers and herbalists have long relied on its potent properties to treat a variety of ailments, believing in its powerful ability to enhance overall health.
Today, modern research is beginning to validate these ancient claims. Scientists have discovered numerous bioactive compounds within Agaricus blazei that show promising potential for improving our health. Through rigorous studies, we are uncovering the mushroom's effects on the immune system, cancer prevention, and more—benefits that were once considered folklore.
In this comprehensive guide, we will delve into the rich history of Agaricus blazei, explore its many health applications, and provide tips on selecting the best Agaricus blazei supplements.
Index
- What are Functional Mushrooms?
- What Is Agaricus Blazei Murrill (ABM)?
- Historic Applications of Agaricus Blazei Murrill (ABM)
- The Science Behind The Benefits Of Agaricus Blazei Murrill (ABM)
- Health Benefits of Agaricus Agaricus Blazei Murrill (ABM)
- How To Buy A Good Quality Agaricus Supplement?
- Dose, Safety, Side Effects
- How To Take Agaricus Blazei Mushrooms For Health Support
- FAQs
What are Functional Mushrooms?
Referred to as 'functional mushrooms', these edible fungi boast a diverse range of bioactive compounds. Each type of functional mushroom possesses a unique bioactive profile, contributing to its ability to support specific bodily systems. Agaricus Blazei Murrill, in particular, stands out for its remarkable capacity to enhance the immune system, among other health benefits.
If you're familiar with functional mushrooms, you've likely encountered the term 'beta-glucans' or 'beta-D-glucans.' These polysaccharides play a crucial role in the immune-modulating effects of mushrooms. A more detailed exploration of Beta-Glucans will be provided in a dedicated section.
What Is Agaricus Blazei Murrill (ABM)?
Agaricus blazei Murrill (ABM) is a species of medicinal mushroom celebrated for both its culinary and therapeutic properties [1]. The mushroom is known by various names such as Cogumelo do sol or medicinel in Brazil, Himematsutake, Agarikusutake, or Kawarihiratake in Japan, and Ji Song Rong in China.
Agaricus originates from Piedade, a small village nestled in the highlands of the Atlantic forest near Tauape, in São Paulo province, Brazil. In 1893, the fungus was initially identified in the United States as Agaricus subrefrescens Peck. Later, in 1947, American taxonomist Dr. Murrill reclassified it and published it under the name Agaricus blazei Murrill. At that time, the Brazilian ‘almond mushroom’ (Agaricus brasiliensis) was already recognized, but no link was made, and they were considered three distinct species.
Detailed studies by researchers Wassermann and Didukh in 2002, along with genome sequence analysis by researcher Kerrigan, revealed that they are the same species. Despite Agaricus subrefrescens Peck being the earliest scientific name, Agaricus blazei Murrill has been more commonly used. Notably, the cultivation of the Brazilian mushroom began with a Japanese mycologist residing in Brazil, leading to its widespread cultivation in many Asian countries since the 1980s.
ABM is a large Agaricus mushroom known for its brownish-gold cap, typically 7 to 12 centimetres wide. It has a rounded, fleshy cap and a short, firm stem [3, 4].
In nature, ABM grows well in places like forests and areas with plant debris and animal waste. It's good at breaking down these materials. Nowadays, ABM is mostly grown in Japan, China, and Brazil. People cultivate it in special soils that are made richer with nutrients and nitrogen-based substances [4].
Historic Applications of Agaricus Blazei Murrill (ABM)
Medicinal mushrooms have a long-standing tradition in traditional Eastern therapies, where hot-water soluble extracts from these mushrooms were historically employed as remedies. This practice likely originated in the Far East. The earliest known historical reference to the medicinal use of mushrooms from the Agaricus genus can be traced back to Byzantine medical treatises in the Mediterranean region, specifically from the 4th to the 15th centuries AD. Orivasios and Apuleius described their use for treating malignant ulcers of the larynx during this period [5].
Historically, Agaricus blazei Murrill has been revered in various cultures for its purported health benefits. Originating from the highland areas of Brazil, ABM gained attention for its traditional use in enhancing overall well-being. It was introduced to Japan in the 1960s, where it was extensively studied for its medicinal potential [2].
In Brazil, ABM has been traditionally believed to fight physical and emotional stress, stimulate the immune system, improve the quality of life in diabetics, reduce cholesterol, prevent osteoporosis and peptic ulcer, treat circulatory and digestive problems and fight cancer [2].
Japanese researchers have experimentally demonstrated the immunostimulant and anticancer effects of ABM extracts, leading to its integration into both dietary and therapeutic practices in Oriental medicine [2].
The Science Behind The Benefits Of Agaricus Blazei Murrill (ABM)
Employing contemporary research methodologies, scientists have ascertained the wealth of benefits associated with Agaricus Blazei Murill (ABM) mushrooms in promoting health and well-being.
This fungus comprises various bioactive compounds, primarily in the form of polysaccharides, glucans, and proteins, all of which play a multifaceted role in supporting various aspects of bodily functions [6, 7, 8].
Polysaccharides
Studies have shown that the polysaccharides present in ABM have various positive effects on the body. These effects include actions against cancer, antioxidant properties, regulation of the immune system, and reducing inflammation [8]. The most significant polysaccharide found in ABM is FIII-2-b, which comprises a protein complex composed of 43.4% protein and 50.2% carbohydrates and is known as a proteoglycan [6].
Proteoglycans are complexes made up of proteins and polysaccharides. This compound has shown apparent antitumor activity and is crucial for the mushroom's health benefits [6].
Beta-Glucans
Beta-glucans are naturally occurring polysaccharide compounds found in the cell walls of certain grains, fungi, bacteria, and other sources. ABM mushrooms are notable for their high content of beta-glucans, particularly those with a (1-6)-β-backbone structure and (1-3)-β-side branches, which are known to enhance immunomodulatory activity [7, 8].
Beta-glucans function as Biological Response Modifiers (BRMs), modulating the immune system and adjusting its activity as needed. These modifiers have the capacity to enhance the immune response, leading to a more effective defence against infections and various other benefits [8, 9, 10]
Alpha-Glucans
In addition to beta-glucans, ABM also contains alpha-glucans, which are found to inhibit tumorigenesis. The water-soluble (1-4)-α-glucan with apparent antitumor activity increases during the maturation of the fruiting bodies, making mature fruiting bodies more beneficial for producing nutraceuticals [19] [8]. Alpha-glucans have shown significant contributions to anticancer activity and are important in maintaining immune system homeostasis [11, 12].
Immunomodulatory Proteins
AbM contains various immunologically active proteins, such as those that stimulate the production of cytokines like TNF-α, IL-8, IL-12, and nitric oxide [13, 14]. These proteins are essential for enhancing the immune system's response to tumours and infections, making ABM a valuable component in immunotherapy [15,16].
Antioxidants
AbM is rich in antioxidants, which help protect the body from oxidative stress and inflammation. Ethanolic extracts of ABM have shown remarkable antioxidative properties, effective in the auto-oxidation of linoleic acid and demonstrating potent antioxidant substances even after heat treatment [17, 18].
AbM also contains phenolic compounds, which include flavonoids and other compounds that provide antioxidant and anti-inflammatory benefits. Isoflavonoids, a subclass of flavonoids, have been found in AbM. These compounds may help lower blood sugar levels and may be helpful for treating diabetes [21].
Other Noteworthy Compounds
AbM contains agaritine and ergosterol (provitamin D2), which have been shown to help kill leukaemia cells [19] and stop the growth of new blood vessels that tumours need [20].
Health Benefits of Agaricus Agaricus Blazei Murrill (ABM)
From traditional uses in Brazilian folk medicine to contemporary scientific research, Agaricus Blazei Murill (AbM) is renowned for its wide-ranging health benefits.
Health Benefits at a Glance
- Agaricus May Help Manage Diabetes
- Agaricus' Anti-Inflammatory Properties
- Agaricus' Anticancer Effects
- Agaricus' Neuroprotective Effects
- Agaricus May Help Treat Hepatitis
- Agaricus May Enhance the Immune System
- Agaricus May Help Lower Cholesterol
- Agaricus in Cosmeceutical Applications
Agaricus May Help Manage Diabetes
Agaricus brasiliensis (which is the same species as Agaricus blazei Murill), native to Brazil and widely cultivated in Japan, is used for treating various conditions, including diabetes.
It contains special sugars called polysaccharides, as well as Beta-D-glucan and Alpha-D-glucan. These substances have been shown to reduce the risk of genetic mutations and boost the immune system, both in lab tests and in living organisms.
For managing diabetes, these natural compounds work in several ways:
- Increasing Plasma Insulin Levels: They help raise the levels of insulin in the blood, which is crucial for controlling blood sugar.
- Enhancing Insulin Sensitivity: They make the body more responsive to insulin, improving the control of blood sugar levels.
- Inhibiting Alpha-Glucosidase Enzymes: By blocking these enzymes in the intestine, they slow down the digestion of carbohydrates, preventing spikes in blood sugar.
- Elevating Hepatic Glycogen Levels: They help store more glucose in the liver as glycogen, making it available when needed and helping to regulate blood sugar.
- Promoting Glucose Utilisation: They encourage the body to use glucose more efficiently in tissues, reducing blood sugar levels.
- Scavenging Free Radicals: They have antioxidant properties that help eliminate harmful free radicals, reducing oxidative stress [22].
Studies have shown that Agaricus blazei Murill extract reduces blood glucose levels in diabetic models and exhibits antioxidant properties that mitigate oxidative stress, suggesting potential therapeutic benefits for diabetes management [23].
Agaricus' Anti-inflammatory Properties
Agaricus blazei Murill is known for its significant anti-inflammatory effects. Research shows that this mushroom can reduce inflammation caused by a high-fat diet in mice by lowering the production of inflammatory substances like TNF-α [24]. This is beneficial because reducing TNF-α helps to decrease overall inflammation in the body, which can prevent chronic diseases related to inflammation, such as heart disease and diabetes.
It also boosts the immune system by increasing the activity of natural killer cells and macrophages [25]. Enhancing the activity of these immune cells is advantageous because it improves the body's ability to fight infections and potentially target cancer cells.
The polysaccharides in AbM have antioxidant properties and help regulate the immune system, which adds to its ability to fight inflammation [26, 27]. Antioxidants are important because they neutralise free radicals, reducing oxidative stress and preventing cell damage, which can lead to various diseases. Immunomodulatory functions help maintain a balanced immune response, ensuring that the immune system is effective but not overactive, which can prevent autoimmune diseases.
Agaricus' Anticancer Effects
Agaricus blazei Murill is traditionally used as an anticancer remedy. It contains polysaccharides that are known to inhibit tumour growth by enhancing immune function [28]. This is beneficial because a stronger immune system can more effectively identify and attack cancer cells.
The compounds in this mushroom, including Beta-D-glucans, ergosterol, and agaritine, have demonstrated antitumor effects in various studies. Agaritine induces apoptosis (cell death) in leukemic cells [29], which is advantageous because it helps eliminate cancerous cells from the body. Beta-D-glucans indirectly inhibit tumour cell growth by boosting immune responses [30]. A heightened immune response can better control and reduce tumour growth.
AbM has shown antitumor activity in models of fibrosarcoma, myeloma, prostate cancer, ovarian cancer, and lung cancer [31]. This wide range of effectiveness is promising as it suggests potential benefits for various types of cancer.
Compounds from Agaricus blazei, such as ergosterol and Beta-D-glucans, have been found to prevent the formation of new blood vessels that tumours need to grow [47-49]. This is beneficial because stopping the growth of these new blood vessels can starve tumours of essential nutrients and oxygen, slowing or stopping their growth.
This property helps in controlling and reducing cancer progression [47-49]. Thus, Agaricus blazei Murill’s ability to inhibit blood vessel formation in tumours is good as it suggests potential for helping to manage and reduce cancer growth.
Furthermore, human studies indicate increased natural killer (NK) cell activity and improved quality of life in cancer patients [32]. Increased NK cell activity is beneficial because NK cells play a crucial role in targeting and destroying cancer cells.
Agaricus' Neuroprotective Effects
Agaricus blazei Murill extract helps protect the myenteric plexus, a network of nerve cells in the digestive system, in animals by maintaining the health of nerve cells and their supporting cells, known as glial cells [31, 33]. This is important because healthy nerve cells and glial cells are crucial for the nervous system's proper functioning, which affects everything from digestion to overall brain health.
When the extract is used over a long period, it helps keep the balance in this network of nerve cells, which suggests it could provide protective benefits to the nervous system [31, 33].
Maintaining this balance could help prevent diseases that damage the nervous system, like neurodegenerative conditions (e.g., Alzheimer’s disease). Additionally, supporting overall brain health can improve cognitive functions and quality of life.
Agaricus May Help Treat Hepatitis
Agaricus blazei Murill has been found to help in treating hepatitis. Clinical studies have shown that it can lower levels of liver enzymes in patients with hepatitis B and improve liver function in animal models with liver damage [34-37]. This is beneficial because lower liver enzyme levels usually indicate less liver damage, and improved liver function means the liver is working better overall.
Additionally, the polysaccharides (complex sugars) in this mushroom boost the immune system and protect liver cells, making it a promising option for managing and treating liver diseases [38]. This is good because it suggests that Agaricus blazei Murill could play a role in supporting liver health and treating hepatitis.
Agaricus May Enhance the Immune System
Agaricus blazei Murill helps enhance the immune system by stimulating several key types of immune cells, including natural killer cells, macrophages, and dendritic cells [39, 40, 41]. This is advantageous because these cells are essential for fighting off infections and cancer.
The mushroom also increases the production of certain molecules that help trigger inflammation, which is a natural part of the immune response to threats like infections and tumours [39, 40, 41].
A stronger immune response can more effectively target and eliminate harmful pathogens and cancer cells. Therefore, this mushroom’s ability to boost immune function is beneficial for supporting overall immune health and defending against diseases [42].
Agaricus May Help Lower Cholesterol
Agaricus blazei Murill can positively affect lipid levels by lowering cholesterol and triglycerides in models with high cholesterol [43, 44]. This is beneficial because lower levels of cholesterol and triglycerides are associated with a reduced risk of heart disease.
The mushroom helps by influencing the genes involved in cholesterol metabolism and promoting the excretion of lipids (fats), which supports cardiovascular health [43-46]. This is good as it indicates that Agaricus blazei Murill could aid in managing cholesterol levels and improving heart health.
Agaricus in Cosmeceutical Applications
Agaricus blazei Murill can be used in cosmetic products [[50]. Its ethanolic extract is safe for applying to the skin and may offer benefits for skin health, making it a valuable ingredient in wellness and skincare products [50].
How To Buy A Good Quality Agaricus Supplement?
Choosing a good quality mushroom supplement can be a daunting task, as there are many options available in the market. However, there are a few key things to consider when selecting a high-quality mushroom supplement.
Fruiting Body vs. Mycelium
Quality control standards for functional mushroom products are currently lacking, highlighting the urgent need for systematic scientific verification of active compounds in these nutritional supplements. This is crucial for ensuring greater accountability regarding ingredient integrity and transparency.
When a product fails to specify the source of its Agaricus, there's a risk that it relies on mycelium (the fungal root structure) rather than the Agaricus fruiting body (the actual mushroom we see above the ground). To ensure the highest quality Agaricus mushroom supplement, it is advisable to choose products with an ingredients label indicating the use of only organic fruiting body, free from mycelium or grain contaminants.
Explore the notable distinctions between supplements crafted from mycelium and those derived from the fruiting body by clicking here.
Beta-Glucan Content
Beta-glucans are one of the primary compounds responsible for Agaricus's unique immune system-supporting function and other health benefits.
Many brands incorporate various starches, fillers, colourings, unnecessary additives, and other ingredients into their supplements, which offer no health benefits. Moreover, these additions suggest a low percentage of actual Agaricus extract in the product, resulting in a diminished concentration of beta-glucans (medicinal compounds) and, consequently, lower therapeutic potency.
To obtain the most potent and high-value functional fungi supplement, scrutinise the product label for specific beta-glucan content. To ensure the optimal quality of your Agaricus mushroom supplement, verify that the product specifies a beta-glucan concentration of at least 25%. This ensures you receive the full spectrum of health benefits associated with this mushroom.
Antioxi's Agaricus Blazei Extract boasts a beta-glucan content exceeding 30%, guaranteeing that you receive the necessary benefits.
Organically Certified
Opt for certified organic options as mushrooms tend to absorb pollutants from their surroundings. Mushrooms that are organically grown refer to mushrooms cultivated in a natural manner, devoid of herbicides, fungicides, or pesticides.
Safety Tests
Heavy metals and pesticide tests are safety tests which will indicate whether mushrooms are safe to consume.
Extraction Method
Understanding the ingredients in your diet is crucial, especially when it comes to functional mushrooms and their quality. Opting for a low-quality mushroom supplement poses a risk to experiencing the full range of potential benefits, making your health a priority.
A key indicator of a high-quality functional mushroom product is its extraction from the mushroom (fruiting body) and using the appropriate method. Three commonly used extraction methods for functional mushrooms are hot water, alcohol, and dual extraction (involving both hot water and alcohol).
The choice of the extraction method can impact the quality, and research indicates that not all methods are equally effective for every mushroom. Some methods may even remove medicinal constituents during the process. Therefore, it is crucial for supplement producers to understand which extraction method ensures maximum benefit and efficacy for their product.
Hot water extraction involves heating the mushroom in water to draw out water-soluble compounds like polysaccharides and beta-glucans. The resulting liquid can be consumed directly or dried to create a powder concentrated with the beneficial compounds.
Alcohol extraction follows a comparable procedure but utilises alcohol instead of water to eliminate non-water-soluble compounds such as triterpenes.
Determining the optimal extraction method, whether hot water or alcohol, depends on the mushroom in question. Antioxi employs a hot water extraction approach for Agaricus Blazei.
Through the extraction processes, the liquids obtained are then evaporated, resulting in a single extract powder. This method ensures the highest potency and health benefits in the final product.
To guarantee the top-notch quality of your Agaricus Blazei mushroom supplement, check whether the product has utilised a hot water extraction method.
Click the link below to learn more about what to look for when choosing a high-quality mushroom supplement.
Read the Supplement Label
To make an informed decision, it’s essential to understand how to read supplement labels correctly. Labels can often be misleading, and knowing what to look for, such as beta-glucan content, fruiting body vs. mycelium, and extraction method, can help you avoid low-quality products.
Please read our full guide on how to decode supplement labels here: How to Read Supplement Labels
Click the link above to learn more about what to look for when choosing a high-quality mushroom supplement.
Dose, Safety, Side Effects
Dose
Baseline Dose
Start with 2 capsules or 1 gram per day for general wellness. This helps you experience the foundational benefits of Lion’s Mane.
Enhanced Dose
For more pronounced effects, please get in touch with us. Our team can help you determine the best approach for your needs.
Flexible Dosage Regimen
Whether you prefer splitting the dose throughout the day or taking it all at once, the choice is yours. For optimal absorption, it is recommended to consume mushrooms on an empty stomach. However, if you have a sensitive constitution, consider splitting the dose and taking it after a meal.
Feeling unsure about where to begin? Schedule your free private online consultation with Marko, our Founder, and discover the perfect products to meet your wellness goals.
Click here to book a free consultation with Marko.
Safety
Individuals with liver disease/dysfunction are advised NOT to use Agaricus Blazei, as it may lead to further detriment of liver function.
Individuals with diabetes are advised to seek guidance from their healthcare provider before incorporating Agaricus Blazei into their diet, as it may impact blood sugar levels.
While some studies suggest that ABM may have anti-inflammatory effects, it can also stimulate the immune system. Therefore, individuals with autoimmune diseases should seek medical guidance before considering the use of Agaricus.
Do not consume Agaricus mushrooms within two weeks of undergoing surgery or if you suffer from a bleeding disorder.
For individuals who are pregnant, breastfeeding, or have an autoimmune disease, it is crucial to consult with a healthcare professional before considering the use of Agaricus Blazei mushrooms.
Do not consume Agaricus Blazei if you are allergic to mushrooms.
MEDICATION INTERACTIONS
While Agaricus Blazei mushrooms boast potential health benefits, it's crucial to be mindful of potential interactions with medications. Understanding how Agaricus Blazei may interact with certain conditions and medications can guide individuals in making informed decisions regarding its inclusion in their routine.
Individuals who are taking the following medications should also consult their healthcare provider before incorporating Agaricus Blazei into their regimen:
- Medications for diabetes management
- Medication for liver disease/dysfunction
- Blood-thinning medications
- Medications to suppress the immune system
If you have any concerns regarding the interaction between Agaricus Blazei and your medications, it's a good idea to discuss it with your healthcare provider. They can offer you the most appropriate guidance.
Please bear in mind that the information we provide is for educational purposes and shouldn't be considered a replacement for professional medical advice.
Your health and safety are important to us, and we want to ensure all our customers use our products to their benefit, not detriment.
Side Effects
In a study, cancer survivors took 1.8, 3.6, or 5.4 grams of ABM granulated powder daily for six months to assess safety. Out of 78 patients, 9 (12%) experienced adverse effects, primarily digestive issues such as nausea and diarrhoea, and one patient had a liver-related allergic reaction. Importantly, these adverse effects were not dose-dependent.
The study concluded that ABM is generally safe for most patients at these dosages, supporting previous evidence of its safety, although there is a potential for allergic reactions [51].
How To Take Agaricus Blazei Mushrooms For Health Support
Powders vs. Capsules
For those with a fast-paced lifestyle, intricate recipes might not be in the cards. That's precisely why Antioxi has crafted an Organic Agaricus Blazei Extract available in convenient capsule form.
If you're a cooking enthusiast or favour the convenience of a powder, our Organic Agaricus Blazei extract in powder form could be an ideal option for you. Our Agaricus Blazei can be seamlessly incorporated into smoothies, stews, coffee and all your other favourite meals and drinks.
It's essential to note that there is no difference in potency between our powdered extracts and capsules. Our capsules contain the exact same powdered extract, guaranteeing uniform effectiveness throughout our product line.
Frequently Asked Questions
Are The Mushrooms Organic?
All of our mushrooms have been organically sourced and certified.
Is It Safe To Consume Medicinal Mushrooms During Pregnancy Or Whilst Breastfeeding?
While medicinal mushrooms can offer some great benefits during pregnancy such as strengthening immune health, improving digestion and of course the much needed energy boost, there is unfortunately not yet enough information regarding studies during pregnancy and whilst breastfeeding where we can confidently give advice.The best would be to consult with your healthcare provider and/or midwife.
Can Children Use Medicinal Mushrooms?
Research regarding the use of medicinal mushrooms by children is still at its infancy. There is however an interesting study conducted in 2018 which investigated the effects of Reishi on immune system cells of 3-5 year olds. [52]
The study showed that Reishi increased immune system cell counts in the peripheral blood, which are crucial for defending against infections. The treatments were also well-tolerated and safe, with no abnormal increases in serum creatinine or hepatic aminotransferases. While the study shows promise in the safety and effectiveness of the use of medicinal mushrooms in children, we do always suggest consulting with your child's doctor prior to introducing anything new into their diet.
If you do get the go ahead we suggest reducing the diet to 1/4 of a dose for young children.
These findings suggest the need for more extended controlled clinical trials to evaluate the effectiveness of medicinal mushrooms in preventing infections in children.
What Is The Difference Between The Powder And Capsules?
There is no difference in terms of benefits. The only difference is preference of use.
What Is The Difference Between Using The 8 Mushroom Blend And Using An Individual Mushroom?
Our 8-blend mushroom product is like an all-in-one health elixir. It's perfect for those seeking overall well-being, boosting digestion, or just looking for a daily health lift.
However, if you're using mushrooms as targeted support for a specific health concern, say, Lion's Mane for cognitive clarity or Reishi for stress relief, the individual route is your best bet.
Are There Any Allergy Precautions/Medication Interactions?
Individuals with liver disease / dysfunction are advised to NOT use Agaricus Blazei, as it may lead to further detriment of liver function.
Individuals with diabetes are advised to seek guidance from their healthcare provider before incorporating Agaricus Blazei into their diet, as it may impact blood sugar levels.
While some studies suggest that ABM may have anti-inflammatory effects, it can also stimulate the immune system. Therefore, individuals with autoimmune diseases should seek medical guidance before considering the use of Agaricus.
Do not consume Agaricus mushrooms within two weeks of undergoing surgery or if you suffer from a bleeding disorder.
For individuals who are pregnant, breastfeeding, or have an autoimmune disease, it is crucial to consult with a healthcare professional before considering the use of Agaricus Blazei mushrooms.
Do not consume Agaricus Blazei if you are allergic to mushrooms.
Individuals who are taking the following medications should also consult their healthcare provider before incorporating Agaricus Blazei into their regimen:
- Medications for diabetes management
- Medication for liver disease / dysfunction
- Blood-thinning medications
- Medications to suppress the immune system
If you have any concerns regarding the interaction between Agaricus Blazei and your medications, it's a good idea to discuss it with your healthcare provider. They can offer you the most appropriate guidance.
Which Mushroom Extraction Do You Use?
The optimal extraction method once again depends on the mushroom itself. Different methods are used to promote and dissolve the unique active ingredients in the mushroom extracts and hence create a high spectrum mushroom extract.
The 3 different extraction methods:
1. Alcohol (ethanol)
This extraction is used to draw out the fat-soluble compounds in the mushrooms, such as the adaptogenic terpenoids.
2. Hot water
This extraction is used to extract the water-soluble compounds, the polysaccharides, and the immunomodulating Beta-D-glucans. The dual extraction process ensures you’re getting the full spectrum of compounds when it comes to a potent mushroom extract
3. Dual extraction
Dual extraction refers to a combination of water and alcohol extraction. The dual extraction process ensures you’re getting the full spectrum of compounds when it comes to a mushroom where the active ingredients benefit from both alcohol and well as a water extract.
Hot water extraction works best for:
- Cordyceps, Turkey Tail, Maitake, Tremella, Shiitake and Agaricus Blazei
- Double (alcohol & water) extraction works best for:
- Lion's Mane, Reishi, Chaga
Do You Use The Fruiting Body Or Mycelium?
We use the Fruiting Body of Agaricus Blazei.
We have a helpful article here which explains the different mushroom parts.
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