Oyster Mushroom

Ultimate Guide to Oyster Mushroom: Health Benefits & Uses

Ultimate Guide to Oyster Mushroom: Health Benefits & Uses Article by Antioxi

Beneath the forest floor, Oyster mushrooms perform a remarkable feat—these unassuming fungi can naturally break down environmental toxins, including certain types of plastic. It’s a surprising ability for a mushroom often found in kitchens around the world, celebrated for its mild flavour and tender texture. But the Oyster mushroom’s talents extend far beyond the environment—it’s also packed with health benefits that have been cherished for centuries.

In this ultimate guide, we’ll take you on a journey through the world of Oyster mushrooms, exploring their fascinating abilities, their many health benefits, and provide tips on how to choose a top-notch Oyster mushroom supplement.

In This Article:

  1. What are Functional Mushrooms?
  2. What are Oyster Mushrooms?
  3. Historical Applications of Oyster Mushrooms
  4. The Science Behind the Benefits of Oyster Mushrooms
  5. Health Benefits of Oyster Mushrooms
  6. How to Buy a Good Quality Oyster Mushroom Supplement?
  7. Dose, Safety, Side Effects
  8. How to Take Oyster Mushrooms for Health Support
  9. Frequently Asked Questions

What are Functional Mushrooms?

Referred to as 'functional mushrooms', these edible fungi boast a diverse range of bioactive compounds. Each type of functional mushroom possesses a unique bioactive profile, contributing to its ability to support specific bodily systems. Oyster mushrooms, in particular, are well-known for their cardiovascular benefits, helping to promote heart health by reducing cholesterol levels and supporting healthy blood pressure.

If you're familiar with functional mushrooms, you've likely encountered the term 'beta-glucans' or 'beta-D-glucans.' These polysaccharides play a crucial role in the immune-modulating effects of mushrooms. A more detailed exploration of Beta-Glucans will be provided in a dedicated section.

What are Oyster Mushrooms?

Oyster mushrooms, scientifically known as Pleurotus ostreatus, are a variety of edible fungi appreciated for their delicate flavour and soft texture when cooked. These mushrooms can be found both in the wild and cultivated across the globe. In natural settings, oyster mushrooms thrive in temperate and subtropical forests, typically growing on decaying trees, logs, or stumps. They play a crucial role in ecosystem processes as saprotrophic organisms, decomposing organic matter and recycling nutrients.

The name "Pleurotus" originates from the Greek word "pleuro," meaning “side ear”, which refers to the lateral attachment of the stem. "Ostreatus," derived from Latin, translates to "oyster-like," highlighting the resemblance of the mushroom cap to an oyster shell. Thus, the scientific name Pleurotus ostreatus signifies a mushroom with a cap shaped akin to an oyster shell, laterally attached to the stem.

Oyster Mushroom Illustration

Other species within the Pleurotus genus are also commonly referred to as oyster mushrooms, thus P. ostreatus is sometimes distinguished as the Tree Oyster Mushroom [1] or the Grey Oyster Mushroom [2] to differentiate it from these other species.

The distinctive appearance of oyster mushrooms further emphasises their name origins. Their cap, typically fan-shaped or oyster-like, exhibits a range of colours including white, grey, brown, or pinkish hues. The gills underneath the cap are often white and closely spaced. Oyster mushrooms are characterised by their rapid growth and prolific fruiting, particularly in moist environments. In both wild and cultivated settings, they serve as a popular choice for culinary purposes due to their mild flavour and versatile culinary applications.

The pictured Pleurotus ostreatus displays a classic fan-shaped cap with wavy margins. Note the closely spaced, white gills on the underside of the cap

History and Applications of Oyster Mushrooms

The oyster mushroom has a rich history dating back to the 17th century in Germany, where it was initially gathered from the wild as a subsistence measure during World War I. By the late 19th century, European countries like France and Germany developed advanced cultivation techniques, leading to more controlled and consistent production. This knowledge spread globally, with Asian countries incorporating oyster mushrooms into their cuisines and establishing them as a culinary staple.

In the 20th century, large-scale commercial production emerged, particularly in China, now a leading producer. Oyster mushrooms are celebrated not only for their delicious flavour but also for their nutritional value, being low in calories and rich in protein, vitamins, and minerals.

Beyond culinary uses, they have been studied for their biotechnological potential, such as in bioremediation and bioconversion.

An example of oyster mushrooms being used in bioremediation and bioconversion is their application in the cleanup of agricultural waste. Oyster mushrooms can break down lignocellulosic materials, which are complex compounds found in plant biomass. For instance, they can decompose straw, sawdust, and corn cobs, converting these agricultural byproducts into simpler, useful substances. In bioremediation, they have been used to degrade pollutants like pesticides and heavy metals from contaminated soils, transforming these harmful substances into less toxic forms.

This ability to degrade and convert complex organic materials makes oyster mushrooms valuable in environmental cleanup and sustainable waste management practices.

The Science Behind the Benefits of Oyster Mushrooms

Similar to other medicinal mushrooms, oyster mushrooms contain a variety of bioactive compounds that contribute to their potential health benefits.

Polysaccharides

Beta Glucans

In the case of oyster mushrooms, the polysaccharides present, particularly beta-glucans, have been a focal point of scientific interest due to their potential health-promoting properties.

Beta-glucans are naturally occurring polysaccharide compounds found in the cell walls of certain grains, fungi, bacteria, and other sources. Beta-glucans play a pivotal role in fostering immune support and various medicinal attributes. Widely recognized as Biological Response Modifiers (BRMs) [3], beta-glucans function by modulating the immune system, adjusting its activity as needed. These modifiers have the capacity to enhance the immune response, leading to a more effective defence against infections and various other benefits.

The beta-D glucans found in oyster mushrooms have shown anti-obesity effects and enhance the digestive system while protecting against metabolic syndromes [4, 5]. A specific beta-glucan named Pleuran also boosts the bodies’ immune response [38, 39].

Sulfated Polysaccharides (PS)

Sulfated polysaccharides found in oyster mushrooms have been found to inhibit blood clot formation through both the intrinsic and extrinsic pathways. This means they can prevent clotting in both the blood vessels and tissues. Additionally, these PS have shown minimal cytotoxicity, indicating that they are unlikely to harm cells [6].

Other Noteworthy Polysaccharides

Another polysaccharide found in oyster mushrooms, namely WPOP-N1, has shown the ability to inhibit tumour growth by elevating the levels of tumour necrosis factor α (TNF-α) and nitric oxide (NO) in animal studies [7].

Lovastatin

Oyster mushrooms have been found to contain lovastatin [8].

Lovastatin found in fungi is a naturally occurring bioactive compound produced as a secondary metabolite by certain fungal species. Its primary function is to inhibit the enzyme HMG-CoA reductase, thereby reducing the synthesis of cholesterol in the organism.

Lovastatin has also been shown to have anti-inflammatory effects. [35, 36]

Other Noteworthy Bioactive Components

Phenolics and flavonoids, ergothioneine, chlorogenic acid, and naringenin: These compounds provide antioxidant activity. [9] [26-30]

Ethyl iso-allocholate, tetracetyl-D-xylonic nitrile, hexadecane (CAS), phytofluene: These compounds possess properties that fight against bacteria and fungi, as well as the ability to kill breast cancer MCF-7 cells. [10]

Gallic acid, trans-cinnamic acid, caffeic, ferulic, aspartic vanillic acid, quercetin:

These compounds display antioxidant effects, function as ACE inhibitors (which help regulate blood pressure), and hinder the growth of human cervical carcinoma cells (HeLa) [11].

Rutin, cinnamic acid, p-coumaric acid and ascorbic acid: The compounds have shown potent anti-inflammatory effects. [34].

Health Benefits of Oyster Mushrooms

Exploring the domains of cardiovascular health and immune function, oyster mushrooms have sparked significant scientific interest. Delve into the compelling evidence that illuminates their potential benefits in these areas.

Health Benefits At a Glance:

    • Oyster Mushrooms Support Heart Health
    • Oyster Mushrooms Support Diabetes Management
    • Oyster Mushrooms’ Antioxidant and Anti-Inflammatory Properties
    • Oyster Mushrooms’ Immune System Support & Antimicrobial Potential

Oyster Mushrooms Support Heart Health

Oyster mushrooms can support cardiovascular health by lowering risk factors such as elevated cholesterol levels and high blood pressure.

Beta-glucans undergo fermentation by gut bacteria, resulting in the production of short-chain fatty acids that aid in lowering cholesterol levels in the body. Notably, P. ostreatus contains double the amount of beta-glucans compared to white button mushrooms (A. bisporus) [13].

Further research indicates that other polysaccharides, called enzymatic residue polysaccharides (EnRPS), can lower bad cholesterol (LDL), total cholesterol, and total triglycerides while raising good cholesterol (HDL) levels.

HDL, or high-density lipoprotein, is often referred to as "good cholesterol" because it helps remove excess cholesterol from the bloodstream, reducing the risk of heart disease. LDL, or low-density lipoprotein, is often referred to as "bad cholesterol" because high levels of LDL can lead to the buildup of plaque in the arteries, increasing the risk of heart disease and stroke. Triglycerides are a type of fat found in your blood, and high levels can increase the risk of heart disease.

The ability of oyster mushrooms to improve these cholesterol levels suggests it could be a valuable food for managing high cholesterol and oxidative stress, which is the damage caused by free radicals that can lead to inflammation and other health problems [14].

In one study, researchers found that giving a high dose (500 mg per kilogram of body weight) of an ultrasound extract of oyster mushroom to rats with high cholesterol significantly lowered their cholesterol and triglyceride levels.

Additionally, the good cholesterol levels increased. This indicates that the extract has properties that help reduce fat levels in the blood (hypolipidemic), combat oxidative stress, and reduce inflammation [15]

Another study showed that obese men who consumed 3 grams of oyster mushroom daily for 90 days saw a reduction in total cholesterol by 12% and LDL by 19%. Lowering cholesterol and LDL can help prevent heart disease and reduce blood pressure [16].

Similarly, research by Khatun and colleagues found that triglycerides and total cholesterol levels dropped by 28% and 8%, respectively, after taking oyster mushrooms, although the levels increased again after stopping the intake for a week. This suggests that consistent consumption might be necessary to maintain the benefits [17].

A small trial in 2011 involving 20 people demonstrated that eating soup with 30 grams of dried oyster mushrooms for 21 days significantly reduced triglycerides, total cholesterol, and oxidised LDL levels [18].

A 2020 review of eight studies involving humans found that consuming oyster mushrooms could help lower blood sugar, triglycerides, blood pressure, and insulin levels, all of which are important for reducing the risk of heart disease [19].

However, the review pointed out that many of the existing studies have a high risk of bias, and more rigorous research is needed to confirm these findings [19].

Oyster Mushrooms Support Diabetes Management

Diabetes mellitus (DM) is a complex condition stemming from issues with insulin production, resistance, or both, leading to high blood sugar levels. Despite advancements in treatment, diabetes rates continue to rise, posing risks of complications and mortality. Seeking alternatives with fewer side effects, many explore traditional remedies like mushrooms.

Studies on oyster mushrooms in diabetic rats revealed significant reductions in fasting blood glucose levels and the activity of enzymes associated with glucose metabolism [20]. The decrease in the activity of enzymes associated with glucose metabolism indicates that oyster mushrooms may influence how the body processes glucose, potentially improving insulin sensitivity and glucose utilisation.

Similarly, fortifying meals with oyster mushroom powder demonstrated benefits in lowering post-meal glucose levels and decreasing free fatty acids in adults with impaired glucose tolerance [21]. Additionally, further research highlighted oyster mushrooms' ability to inhibit an enzyme involved in glucose breakdown [22].

Moreover, oyster mushrooms may aid in blood sugar regulation.

A study involving 22 individuals with and without type 2 diabetes found that consuming powdered oyster mushrooms reduced post-meal blood sugar levels, possibly by enhancing sugar utilisation in body tissues and inhibiting certain blood sugar-elevating proteins [19, 23].

Similarly, a trial with 30 hospitalised individuals with type 2 diabetes showed that consuming cooked oyster mushrooms daily for a week significantly lowered fasting and post-meal blood sugar levels, along with reducing blood pressure, cholesterol, and triglycerides [19, 24].

Furthermore, a study involving 27 men with type 2 diabetes and high blood pressure revealed that daily intake of powdered oyster mushrooms for three months significantly reduced haemoglobin A1c (HbA1c), a marker for long-term blood sugar control [19, 25]. Reducing haemoglobin A1c (HbA1c) levels is good because it indicates better long-term blood sugar control. HbA1c is a measure of average blood sugar levels over the past two to three months, providing valuable insight into how well blood sugar has been managed over time. Lowering HbA1c levels is associated with a decreased risk of diabetes-related complications, such as cardiovascular disease, kidney disease, and nerve damage.

A review in 2020 suggested that these blood sugar-lowering effects might be attributed to oyster mushrooms' high content of beta-glucans, a type of fibre that slows down carbohydrate digestion and absorption [19]. These studies highlight the potential of oyster mushrooms as a natural approach to managing blood sugar levels, offering hope for those with diabetes.

Oyster Mushrooms’ Antioxidant and Anti-Inflammatory Properties

Antioxidant

As mentioned previously, oyster mushrooms are rich in antioxidants, compounds that combat cellular damage in the body. Cellular damage, also known as oxidative stress, occurs when there's an imbalance between the production of harmful molecules called free radicals and the body's ability to neutralise them with antioxidants. When free radicals accumulate, they can damage important cellular components like DNA, proteins, and lipids. This damage can lead to various health problems, including inflammation, accelerated ageing, and increased risk of chronic diseases such as cancer, heart disease, and neurodegenerative disorders

Studies have identified several antioxidant compounds in oyster mushroom extracts, such as phenolics and flavonoids, gallic acid, chlorogenic acid, and naringenin, which help neutralise harmful free radicals [9, 26-29]. Additionally, these mushrooms contain ergothioneine, an amino acid known for its potent antioxidant properties [30].

 
Research in rodents has shown that treatment with oyster mushroom extract can enhance antioxidant levels and reduce markers of inflammation, such as malondialdehyde (MDA) [31]. Another study observed that oyster mushroom extract exhibited antioxidant effects and protected against liver damage caused by toxic chemicals [32]. Furthermore, a test-tube study found that extract from grey oyster mushrooms inhibited oxidative damage to human artery cells and prevented the oxidation of LDL cholesterol, a process implicated in the development of heart disease [33].

Anti-Inflammatory

In addition to their antioxidant properties, oyster mushrooms possess anti-inflammatory effects. Active compounds like rutin, cinnamic acid, p-coumaric acid, and ascorbic acid found in these mushrooms demonstrate potential antioxidant and anti-inflammatory activity [34]. Moreover, compounds like lovastatin and pleuran (beta-glucans) found in oyster mushroom species exhibit potent anti-inflammatory effects [35,36].

Oral administration of freeze-dried powdered oyster mushrooms in rats significantly suppressed inflammation by reducing the secretion of inflammatory markers and inhibiting the activation of inflammatory pathways [37].
These findings suggest that incorporating oyster mushrooms into the diet could offer effective anti-inflammatory benefits with fewer side effects.

Oyster Mushrooms’ Immune System Support & Antimicrobial Potential

Immune System Support

Oyster mushrooms exhibit multifaceted effects on immune function and protection against infections and viruses.

Pleuran, a beta-glucan fibre derived from oyster mushrooms, exhibits immune-modulating properties and shows promise in potentially combating viruses and bacteria. [38, 39].

Studies have shown that supplementation with pleuran, along with vitamin C and zinc, can improve symptoms of herpes simplex virus type 1 (HSV-1) and reduce respiratory symptoms more effectively than vitamin C alone [38]. Additionally, pleuran treatment has demonstrated efficacy in reducing recurrent respiratory tract infections in children and lowering the incidence of upper respiratory tract infections in athletes [39,40].


Furthermore, oyster mushroom extract supplementation has been found to enhance immune function by increasing interferon-γ (IFN-γ) production, a crucial molecule in defending against infections [41]. These immune-modulating effects are attributed to compounds like lectins, β-glucans, and polysaccharide-protein complexes found in oyster mushrooms, which enhance various aspects of immune response [42, 43].

Another study revealed that extracts of oyster mushrooms help to increase the secretion of pro-inflammatory cytokines such as TNF-α and IL-6. It also stimulates the production of inducible nitric oxide synthase (iNOS) and enhances nitric oxide (NO) secretion [44]. Increasing the secretion of pro-inflammatory cytokines helps to activate the immune system, which is crucial for fighting off infections and healing injuries. Nitric oxide plays a role in widening blood vessels, improving blood flow, and regulating blood pressure. It also has antimicrobial properties and is involved in the immune response.

Antimicrobial Potential

In addition to immune support, oyster mushrooms possess antimicrobial properties. Extracts from oyster mushrooms, such as PoPE (P. ostreatus polar extract), have shown promise in inhibiting the growth of harmful bacteria like Staphylococcus aureus and fungi like Candida albicans [10].

These findings underscore the potential of oyster mushrooms as a natural means of bolstering the immune system and protecting against microbial infections, highlighting their value as a dietary supplement or functional food for promoting overall well-being.

Oyster Mushrooms’ Antitumor Potential

The oyster mushroom demonstrates cytotoxic effects, meaning it has the ability to kill or inhibit the growth of cells, particularly cancer cells, more effectively than other mushroom species. This suggests its potential as a natural anti-cancer agent. Furthermore, water-soluble compounds called proteoglycans found in the mycelium (the vegetative part) of this mushroom species exhibit antitumor and immunomodulating effects, meaning they can help modulate the immune system's response to cancer cells, potentially enhancing the body's ability to fight cancer [45].

A study conducted in Japan on 36 499 men indicates that regular consumption of mushrooms, including oyster mushrooms, may reduce the risk of prostate cancer [46]. This finding is significant because it suggests that incorporating mushrooms into the diet could be a simple dietary strategy for reducing the risk of a common cancer. The presence of L-ergothioneine, a naturally occurring antioxidant, in significant amounts in oyster mushrooms may contribute to their potential protective effect against prostate cancer.

Another study explored the effectiveness of an ethanolic extract of P. ostreatus (EEPO) against the growth and proliferation of MCF-7 cells, a commonly studied model of breast cancer [47]. Their findings revealed significant anticancer activity of oyster mushrooms, including inhibition of cell growth and induction of apoptosis (programmed cell death) in cancer cells. This suggests that oyster mushrooms could be a valuable natural source of anticancer agents.

The molecular docking analysis in their study revealed that certain compounds found in oyster mushrooms have a strong affinity for binding with proteins associated with cancer progression. This suggests potential ways in which these compounds may operate within the body to potentially inhibit or slow down the advancement of cancer.

These findings highlight the promising potential of oyster mushrooms in cancer therapy, offering a natural and potentially effective alternative or adjunct to conventional treatments.

How to Buy a Good Quality Oyster Mushroom Supplement?

Choosing a good quality mushroom supplement can be a daunting task, as there are many options available in the market. However, there are a few key things to consider when selecting a high-quality mushroom supplement:

Fruiting Body vs. Mycelium

Quality control standards for functional mushroom products are currently lacking, highlighting the urgent need for systematic scientific verification of active compounds in these nutritional supplements. This is crucial for ensuring greater accountability regarding ingredient integrity and transparency.

When a product fails to specify the source of its oyster mushroom, there's a risk that it relies on mycelium (the fungal root structure) rather than the oyster mushroom fruiting body (the actual mushroom we see above the ground). To ensure the highest quality oyster mushroom supplement, it is advisable to choose products with an ingredients label indicating the use of only organic fruiting body, free from mycelium or grain contaminants.

Explore the notable distinctions between supplements crafted from mycelium and those derived from the fruiting body by clicking here.

Beta-Glucan Content

Beta-glucans are one of the primary compounds responsible for the unique immune system-supporting function and other health benefits of oyster mushrooms.

Many brands incorporate various starch, fillers, colourings, unnecessary additives, and other ingredients into their supplements, which offer no health benefits. Moreover, these additions suggest a low percentage of actual oyster mushroom extract in the product, resulting in a diminished concentration of beta-glucans (medicinal compounds) and, consequently, lower therapeutic potency.

To obtain the most potent and high-value functional fungi supplement, scrutinise the product label for specific beta-glucan content. To ensure the optimal quality of your oyster mushroom supplement, verify that the product specifies a beta-glucan concentration of at least 25%. This ensures you receive the full spectrum of health benefits associated with this mushroom.

Antioxi’s oyster mushroom extract boasts a beta-glucan content exceeding 30%, guaranteeing that you receive the necessary benefits.

Organically Certified

Opt for certified organic options as mushrooms tend to absorb pollutants from their surroundings. Mushrooms that are organically grown refer to mushrooms cultivated in a natural manner, devoid of herbicides, fungicides, or pesticides.

Safety Tests

Heavy metals and pesticide tests are safety tests which will indicate whether mushrooms are safe to consume.

Extraction Method

Understanding the ingredients in your diet is crucial, especially when it comes to functional mushrooms and their quality.

A key indicator of a high-quality functional mushroom product is its extraction from the mushroom (fruiting body) and using the appropriate extraction method. Three commonly used extraction methods for functional mushrooms are hot water, alcohol, and dual extraction (involving both hot water and alcohol).

The choice of the extraction method can impact the quality, and research indicates that not all methods are equally effective for every mushroom. Some methods may even remove medicinal constituents during the process. Therefore, it is crucial for supplement producers to understand which extraction method ensures maximum benefit and efficacy for their product.

To maintain elevated beta-glucan levels in oyster mushrooms, Antioxi employs the hot water extraction method.

To guarantee the top-notch quality of your oyster mushroom supplement, check whether the product has utilised a hot water extraction method.

Click the link below to learn more about what to look for when choosing a high-quality mushroom supplement.

Learn More

Read the Supplement Label

To make an informed decision, it’s essential to understand how to read supplement labels correctly. Labels can often be misleading, and knowing what to look for—such as beta-glucan content, fruiting body vs. mycelium, and extraction method—can help you avoid low-quality products.

Read our full guide on how to decode supplement labels here: How to Read Supplement Labels

Click the link above to learn more about what to look for when choosing a high-quality mushroom supplement.

Dose, Safety, Side Effects

Dose

Baseline Dose

Start with 2 capsules or 1 gram per day for general wellness. This helps you experience the foundational benefits of Lion’s Mane.

Enhanced Dose

For more pronounced effects, please get in touch with us. Our team can help you determine the best approach for your needs.

Flexible Dosage Regimen

Whether you prefer splitting the dose throughout the day or taking it all at once, the choice is yours. For optimal absorption, it is recommended to consume mushrooms on an empty stomach. However, if you have a sensitive constitution, consider splitting the dose and taking it after a meal.

Feeling unsure about where to begin? Schedule your free private online consultation with Marko, our Founder, and discover the perfect products to meet your wellness goals. Click here to book a free consultation with Marko.

Safety

Pregnant and breastfeeding women, as well as individuals with underlying health conditions including mushroom allergy, should consult a healthcare practitioner before consuming oyster mushrooms.

Medication Interactions

While oyster mushrooms boast potential health benefits, it's crucial to be mindful of potential interactions with medications. It is advised to wait at least an hour after taking prescription medication before consuming oyster mushrooms.

Individuals who are taking the following medications should also consult their healthcare provider before incorporating oyster mushrooms into their regimen:

  • Medications for diabetes management
  • Blood-thinning medications
  • Medication for auto-immune diseases

If you have any concerns regarding the interaction between oyster mushrooms and your medications, it's a good idea to discuss it with your healthcare provider. They can offer you the most appropriate guidance.

Please bear in mind that the information we provide is for educational purposes and shouldn't be considered a replacement for professional medical advice.

Your health and safety are important to us and we want to ensure all our customers use our products to their benefit, not detriment.

Side Effects

Consuming certain varieties of edible mushrooms, particularly in significant amounts, may lead to gastrointestinal issues such as nausea, flatulence, diarrhoea, or stomach discomfort. However, whether oyster mushrooms can induce these symptoms remains uncertain [48].

How to Take Oyster Mushrooms for Health Support

Powders vs. Capsules

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For those with a fast-paced lifestyle, intricate recipes might not be in the cards. That's precisely why Antioxi has crafted an Organic Oyster Mushroom Extract available in convenient capsule form.

If you're a cooking enthusiast or favour the convenience of a powder, our Organic Oyster Mushroom Extract in powder form could be an ideal option for you. Our oyster mushroom can be seamlessly incorporated into smoothies, stews, coffee and all your other favourite meals and drinks.

It's essential to note that there is no difference in potency between our powdered extracts and capsules. Our capsules contain the exact same powdered extract, guaranteeing uniform effectiveness throughout our product line.

Frequently Asked Questions

Are the Mushrooms Organic?

All of our mushrooms have been organically sourced and certified.
Is It Safe To Consume Medicinal Mushrooms During Pregnancy or whilst

Breastfeeding?

While medicinal mushrooms can offer some great benefits during pregnancy such as strengthening immune health, improving digestion and of course the much needed energy boost, there is unfortunately not yet enough information regarding studies during pregnancy and whilst breastfeeding where we can confidently give advice.

The best would be to consult with your healthcare provider and/or midwife.

Can Children Use Medicinal Mushrooms?

Research regarding the use of medicinal mushrooms by children is still at its infancy. There is however an interesting study conducted in 2018 which investigated the effects of Reishi on immune system cells of 3-5 year olds. [49]
The study showed that Reishi increased immune system cell counts in the peripheral blood, which are crucial for defending against infections. T

he treatments were also well-tolerated and safe, with no abnormal increases in serum creatinine or hepatic aminotransferases. While the study shows promise in the safety and effectiveness of the use of medicinal mushrooms in children, we do always suggest consulting with your child's doctor prior to introducing anything new into their diet.

If you do get the go ahead we suggest reducing the diet to 1/4 of a dose for young children.

These findings suggest the need for more extended controlled clinical trials to evaluate the effectiveness of medicinal mushrooms in preventing infections in children.

What is the difference between the Powder and Capsules?

There is no difference in terms of benefits. The only difference is preference of use.

What is the difference between using the 8 Mushroom Blend and using an individual mushroom?

Our 8-blend mushroom product is like an all-in-one health elixir. It's perfect for those seeking overall well-being, boosting digestion, or just looking for a daily health lift.

However, if you're using mushrooms as targeted support for a specific health concern, say, Lion's Mane for cognitive clarity or Reishi for stress relief, the individual route is your best bet.

Are There Any Allergy Precautions/Medication Interactions?

Pregnant and breastfeeding women, as well as individuals with underlying health conditions including mushroom allergy, should consult a healthcare practitioner before consuming oyster mushrooms.

Individuals who are taking the following medications should also consult their healthcare provider before incorporating oyster mushrooms into their regimen:

  • Medications for diabetes management
  • Blood-thinning medications
  • Medication for auto-immune diseases

If you have any concerns regarding the interaction between oyster mushrooms and your medications, it's a good idea to discuss it with your healthcare provider. They can offer you the most appropriate guidance.

Which Mushroom Extraction do you use?

The optimal extraction method once again depends on the mushroom itself. Different methods are used to promote and dissolve the unique active ingredients in the mushroom extracts and hence create a high spectrum mushroom extract.

The 3 different extraction methods:

1. Alcohol (ethanol)

This extraction is used to draw out the fat-soluble compounds in the mushrooms, such as the adaptogenic terpenoids.

2. Hot water

This extraction is used to extract the water-soluble compounds, the polysaccharides, and the immunomodulating Beta-D-glucans.

3. Dual extraction

Dual extraction refers to a combination of water and alcohol extraction. The dual extraction process ensures you’re getting the full spectrum of compounds when it comes to a mushroom where the active ingredients benefit from both alcohol and well as a water extract.

Hot water extraction works best for:

  • Cordyceps, Turkey Tail, Maitake, Tremella & Oyster Mushroom
  • Double (alcohol & water) extraction works best for:
  • Lion's Mane, Reishi, Chaga

Do you use the Fruiting Body or Mycelium?

We use the fruiting body of Oyster mushrooms.

References

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Chamutpong, S., Pummarin, T., Noysang, C., et al. (2019). Nutritional properties, antioxidant and anti-acetylcholinesterase activities of Pleurotus ostreatus. Applied Mechanics and Materials, 891, 14-20. 

Rizkyana, A. D., Truc, C. H., Vikash, C. R., et al. (2022). Sulfation and characterization of polysaccharides from oyster mushroom (Pleurotus ostreatus) extracted using subcritical water. Journal of Supercritical Fluids, 179, Article 105412. 

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Hamad, D., El-Sayed, H., Ahmed, W., et al. (2022). GC-MS analysis of potentially volatile compounds of Pleurotus ostreatus polar extract: In vitro antimicrobial, cytotoxic, immunomodulatory, and antioxidant activities. Frontiers in Microbiology, 13, 396. 

Goswami, B., Majumdar, S., Dutta, R., et al. (2022). Optimization of enzymatic hydrolysis of Pleurotus ostreatus derived proteins through RSM and evaluation of nutritional and functional qualities of mushroom protein hydrolysates. Brazilian Journal of Food Technology, 25, e18620. 

Mishra, V., Tomar, S., Yadav, P., et al. (2022). Elemental analysis, phytochemical screening and evaluation of antioxidant, antibacterial and anticancer activity of Pleurotus ostreatus through in vitro and in silico approaches. Metabolites, 12(9), 821. 

Anandhi, R., Annadurai, T., Anitha, T. S., Muralidharan, A. R., Najmunnisha, K., Nachiappan, V., Thomas, P. A., & Geraldine, P. (2013). Antihypercholesterolemic and antioxidative effects of an extract of the oyster mushroom, Pleurotus ostreatus, and its major constituent, chrysin, in Triton WR-1339-induced hypercholesterolemic rats. Journal of physiology and biochemistry, 69(2), 313–323. 

Dong, Y., Zhang, J., Gao, Z., et al. (2019). Characterization and anti-hyperlipidemia effects of enzymatic residue polysaccharides from Pleurotus ostreatus. International Journal of Biological Macromolecules, 129, 316-325. 

Amirullah, N. A., Abidin, N. Z., Abdullah, N., et al. (2021). The ultrasound extract of Pleurotus pulmonarius (Fr.) Quél alleviates metabolic syndromes in hyperlipidaemic Wistar-Kyoto rats fed with a high-fat diet. Biocatalysis and Agricultural Biotechnology, 34, Article 102019. 

Choudhury, B. K., Rahman, T., Kakon, A. J., et al. (2013). Effects of Pleurotus ostreatus on blood pressure and glycemic status of hypertensive diabetic male volunteers. Bangladesh Journal of Medical Biochemistry, 6(1), 5-10. 

Khatun, K., Mahtab, H., Khanam, P. A. (2007). Oyster mushroom reduced blood glucose and cholesterol in diabetic subjects. Mymensingh Medical Journal, 16(1), 94-99. 

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Henao SLD, Urrego SA, Cano AM, Higuita EA. Randomized Clinical Trial for the Evaluation of Immune Modulation by Yogurt Enriched with β-Glucans from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), in Children from Medellin, Colombia. Int J Med Mushrooms. 2018;20(8):705-716. doi: 10.1615/IntJMedMushrooms.2018026986. PMID: 30317947.


 

 

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